CLA is a naturally occurring trans isomer of linoleic acid. It is unique in structure because of the location of the double bonds in the linoleic acid molecule. Pure Encapsulations’ concentrated, improved-potency CLA provides an average of 77% total CLA, and contains the main isomers c9,t11 and t10,c12. Recent research shows that the specific isomers c9,t11 and t10,c12 play key roles in many of CLA’s physiological properties.
CLA may benefit body composition when used as part of a healthy weight management program that includes a reduction in dietary calories with increased physical activity. In a preliminary human study involving 60 overweight subjects, conjugated linoleic acid reduced body fat mass when combined with a standard physical training program. Several animal studies have explored possible mechanisms of CLA, including the ability to moderate fat deposition, increase lipolysis in adipocytes, reduce energy intake, increase energy expenditure and support metabolic rate